Siamak

╭∩╮( ͡° ͜ʖ ͡°)╭∩╮
Aug 13, 2013
22,580
You do know 23andMeh went bankrupt, sold the company, and all their assets are now people’s DNA information, right?

Just saying I’m not sure it’s more than a scam then as now.
I didn’t know that. Actually, I took a test about three weeks ago from an Iranian company, and the result shocked me a bit. 23andMe and other major international companies also don’t offer direct services to Iran due to sanctions and shipping restrictions.
 

JuveJay

The New Normal
Moderator
Mar 6, 2007
78,015
I didn’t know that. Actually, I took a test about three weeks ago from an Iranian company, and the result shocked me a bit. 23andMe and other major international companies also don’t offer direct services to Iran due to sanctions and shipping restrictions.
What were you surprised about?
 

Siamak

╭∩╮( ͡° ͜ʖ ͡°)╭∩╮
Aug 13, 2013
22,580
What were you surprised about?
The results are in Persian, so I'll translate the summary into English. I'd rather take the test through an international institute or company at a price that fits my budget, I just don't know enough about them to take a test and compare their results.
The genetic ancestry profile shows a predominantly West Asian background, with additional Southern European and Balkan genetic affinities.
55% — Iranian, Caucasian & Mesopotamian
35% — Southern European / Mediterranean, primarily Italian & Greek
10% — Balkan
Paternal Haplogroup: R1a-Z93
Overall, the profile indicates a strong genetic connection to the Iranian Plateau, Caucasus, and Mesopotamia, combined with significant genetic affinities toward Southern Europe and the Balkans. The paternal lineage (R1a-Z93) reflects only the direct male line and does not represent the individual's overall genetic background.
 

Juve-Fan-Iraq

Senior Member
Oct 7, 2023
3,889
The results are in Persian, so I'll translate the summary into English. I'd rather take the test through an international institute or company at a price that fits my budget, I just don't know enough about them to take a test and compare their results.
I did mine many years ago before their data breach and it was about 70% Mesopotamian and 20% peninsular arab. Rest is Anatolian, african, and some central Asian. I was kind of surprised to see so little turkish in the makeup honestly. It put me in the general area within iraq. Right now I don't trust these companies, not that it matters anymore since our data has been sold years ago but I thought the reports were interesting at the time. I don't really know if genealogy works for people in our countries because not a lot of records are well maintained either.
 

Siamak

╭∩╮( ͡° ͜ʖ ͡°)╭∩╮
Aug 13, 2013
22,580
I did mine many years ago before their data breach and it was about 70% Mesopotamian and 20% peninsular arab. Rest is Anatolian, african, and some central Asian. I was kind of surprised to see so little turkish in the makeup honestly. It put me in the general area within iraq. Right now I don't trust these companies, not that it matters anymore since our data has been sold years ago but I thought the reports were interesting at the time. I don't really know if genealogy works for people in our countries because not a lot of records are well maintained either.
The most reputable institutes and companies are also at risk of security weaknesses, data breaches, or data leaks. This is inevitable, and it happens frequently to well‑known companies in every field. Basically, no company reports a precise result without the possibility of error or a 100% accurate output. I can’t directly access AncestryDNA, FamilyTreeDNA, or MyHeritage which are well‑known in this field and take a test unless I spend a huge amount of money and travel to another country. But I don’t think their test results would differ much from the sample test I took from a domestic company, aside from possible errors and the lack of a completely definitive result.
 

swag

L'autista
Administrator
Sep 23, 2003
86,052
I didn’t know that. Actually, I took a test about three weeks ago from an Iranian company, and the result shocked me a bit. 23andMe and other major international companies also don’t offer direct services to Iran due to sanctions and shipping restrictions.
Yeah...

https://www.hhrjournal.org/2025/06/...uman-rights-crisis-in-the-23andme-bankruptcy/


DNA is a weird one. I remember 10+ years ago when people in SF were "doing the swab" like it was a rite of passage for socialites to discuss at cocktail parties.

I get being curious about your genetic lineage. But people are handing over very personal data and a whole lot more, which didn't add up for me.

23andMeh started with a business model that they could collect a huge human genome database and use it to help diagnose and detect potential genetic linkages to illnesses, diseases, health risks, etc. But the data science was never that good.

Then things got weird. A decade ago I worked at an "exponential think tank" in Silicon Valley, and the eacc leaders offered employees the benefit of having their full genomes scanned as part of employee benefits. A lot of my coworkers were like, "Yeah, sign me up!"

I asked a good friend who got her PhD in genetics at Harvard who worked at a human genome database lab, and she was like, "Why the hell would anyone do that?" :D It was funny. She pointed out how there's so much of the genome we don't understand, and all you're going to do is make people freak out that they have genetic mutations (as naturally occur) and worry all their life that something could be wrong with zero evidence that there is and nothing that they could do about it.

There is truth in TMI (too much information) in health. Which is why I am so cynical about all these Oura and other health rings that are trying to IPO. They're seling a belief that collecting more irrelevant data wards off harms from ever reaching you, and they create a dependent psychology where these tools and busy boxes of data streams manifest non-existent physical health problems as debilitating mental health problems in the user.
 

mjromeo81

Senior Member
Aug 29, 2022
2,136
There is truth in TMI (too much information) in health. Which is why I am so cynical about all these Oura and other health rings that are trying to IPO. They're seling a belief that collecting more irrelevant data wards off harms from ever reaching you, and they create a dependent psychology where these tools and busy boxes of data streams manifest non-existent physical health problems as debilitating mental health problems in the user.
This.

I know people who get a good night's sleep and wake up feeling fine. Then they check the "data", which tells them their sleep was interrupted and poor quality. Suddenly they're stressed, and they spend the rest of the day convinced they slept terribly. There's even a name for it (orthosomnia).

I am shocked at the amount of fauxductivity products on the market, and just how much people waste their time and money with useless information that will only cause decision paralysis, self-doubt, and decreased confidence in your existing decisions.
 

swag

L'autista
Administrator
Sep 23, 2003
86,052
This.

I know people who get a good night's sleep and wake up feeling fine. Then they check the "data", which tells them their sleep was interrupted and poor quality. Suddenly they're stressed, and they spend the rest of the day convinced they slept terribly. There's even a name for it (orthosomnia).

I am shocked at the amount of fauxductivity products on the market, and just how much people waste their time and money with useless information that will only cause decision paralysis, self-doubt, and decreased confidence in your existing decisions.
As a juvenile diabetic for over 30 years, I get it. Human psychology is weird in that you can feel great, but the moment you see a poor health number at random, it's like getting an 'F' on your report card and your mood turns to crap.

As a T1D, I've been living the "quantified life" for medical reasons for a long time. Which is why I don't get able-bodied Walking Worried types with so much time, money, and privilege that they need to invent new health problems to solve. Somehow they decide it's a great idea to cosplay my chronic illness lifestyle.
 

Siamak

╭∩╮( ͡° ͜ʖ ͡°)╭∩╮
Aug 13, 2013
22,580
Yeah...

https://www.hhrjournal.org/2025/06/...uman-rights-crisis-in-the-23andme-bankruptcy/


DNA is a weird one. I remember 10+ years ago when people in SF were "doing the swab" like it was a rite of passage for socialites to discuss at cocktail parties.

I get being curious about your genetic lineage. But people are handing over very personal data and a whole lot more, which didn't add up for me.

23andMeh started with a business model that they could collect a huge human genome database and use it to help diagnose and detect potential genetic linkages to illnesses, diseases, health risks, etc. But the data science was never that good.

Then things got weird. A decade ago I worked at an "exponential think tank" in Silicon Valley, and the eacc leaders offered employees the benefit of having their full genomes scanned as part of employee benefits. A lot of my coworkers were like, "Yeah, sign me up!"

I asked a good friend who got her PhD in genetics at Harvard who worked at a human genome database lab, and she was like, "Why the hell would anyone do that?" :D It was funny. She pointed out how there's so much of the genome we don't understand, and all you're going to do is make people freak out that they have genetic mutations (as naturally occur) and worry all their life that something could be wrong with zero evidence that there is and nothing that they could do about it.

There is truth in TMI (too much information) in health. Which is why I am so cynical about all these Oura and other health rings that are trying to IPO. They're seling a belief that collecting more irrelevant data wards off harms from ever reaching you, and they create a dependent psychology where these tools and busy boxes of data streams manifest non-existent physical health problems as debilitating mental health problems in the user.
Genetic research is mainly about tracing lineage and understanding how closely related people from a particular ethnic group, country, or geographic region are regardless of how accurate or error the results might be. Because of scientific limitations, historical evidence, and the loss or distortion of historical records over time, genetics is now used to trace ancestry and to sample historical artifacts for genetic research, so it can also be applied to history.
There are laws to protect data such as GDPR in Europe but the fact that these companies sell data, or that data becomes public for any reason, can happen in any field and anywhere like leaks of national ID cards, birth certificates or leak of electronic bank card like paypal, master card and so on.
What fascinates me is knowing which ethnic lineage or which region’s people I’m related to or, based on these genetic tests, which geographic region my ancestors came from.
 

Juve-Fan-Iraq

Senior Member
Oct 7, 2023
3,889
Yeah...

https://www.hhrjournal.org/2025/06/...uman-rights-crisis-in-the-23andme-bankruptcy/


DNA is a weird one. I remember 10+ years ago when people in SF were "doing the swab" like it was a rite of passage for socialites to discuss at cocktail parties.

I get being curious about your genetic lineage. But people are handing over very personal data and a whole lot more, which didn't add up for me.

23andMeh started with a business model that they could collect a huge human genome database and use it to help diagnose and detect potential genetic linkages to illnesses, diseases, health risks, etc. But the data science was never that good.

Then things got weird. A decade ago I worked at an "exponential think tank" in Silicon Valley, and the eacc leaders offered employees the benefit of having their full genomes scanned as part of employee benefits. A lot of my coworkers were like, "Yeah, sign me up!"

I asked a good friend who got her PhD in genetics at Harvard who worked at a human genome database lab, and she was like, "Why the hell would anyone do that?" :D It was funny. She pointed out how there's so much of the genome we don't understand, and all you're going to do is make people freak out that they have genetic mutations (as naturally occur) and worry all their life that something could be wrong with zero evidence that there is and nothing that they could do about it.

There is truth in TMI (too much information) in health. Which is why I am so cynical about all these Oura and other health rings that are trying to IPO. They're seling a belief that collecting more irrelevant data wards off harms from ever reaching you, and they create a dependent psychology where these tools and busy boxes of data streams manifest non-existent physical health problems as debilitating mental health problems in the user.
The Oura ads are so cringe...
 

Wings

Banter era connoiseur
Contributor
Jul 15, 2002
23,588
Sprints are problematic for the simple fact that they never let up. Sprints are not simply shorter deadlines, encountered sporadically as you move along. They are forever repeating, back-to-back deadlines. Waterfall was structured around genuine deadlines and real-world events that demanded focused attention. You worked hard to get something working, then you were done. High pressure was followed by low pressure. Sprints, on the other hand, are fake deadlines, invented for the sake of a process. Since they are contrived, they have no natural breaks or resting periods. There is no time to breathe. There is no autonomy.

When a sprint begins, the expectation is that the time for preparation has passed, and only implementation remains. Scrum seems to assume you can simply "bang it out" like assembling a fucking piece of IKEA furniture. Just pull the next instruction manual from the backlog and follow the steps. In reality, it's more like being dropped into the jungle without a map or provisions, with only two weeks to find your way out.
We resorted to creating 'discovery' tickets for everything then have a briefing to determine if it's worth doing the work. Created a buffer for the rushing to the endless finishing line.
 

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